Is Hashimoto’s Hypothyroidism Genetic
Chronic Autoimmune Thyroiditis or Hashimoto’s Thyroiditis(HT) is an inflammatory disease characterized by diffuse lymphocytic infiltration, fibrosis, and parenchymal atrophy. Hashimoto’s Thyroiditis is the most common cause of primary - Functional Medicine Doctor Houston hypothyroidism which continues to be a common problem, especially in women. Circulating autoantibodies against thyroglobulin and thyroid peroxidase (TPO) were present in almost all patients with autoimmune hypothyroidism. Thyroid Stimulating Hormone Receptor Antibody (TSH-R Ab) blocks the receptor instead of stimulating it as in graves’ diseases. In some cases of Hashimoto’s Thyroiditis, the exact mechanisms underlying autoimmune thyroiditis are not fully understood. The hypothesis relies on both genetic and environmental involvement. Clinically, the disease can present as gradual thyroid failure, with or without goitre formation due to autoimmune-mediated apoptosis of the thyroid epithelial cells. T...